Up to 15% of all strokes occur in hospitalized patients, many of whom are there for surgical procedures or cardiac disorders. Outcomes can be poor, with high mortality - possibly related to co-morbidities and the complexities of hospital care. Risk factors for in-hospital stroke include specific operations and procedures (such as cardiac surgery), previous medical disorders (especially a history of stroke or transient ischemic attack), and certain physiological characteristics (including fever and dehydration). More rapid diagnosis and evaluation for interventional therapies is needed. This major new book examines the causes of treatment-related stroke in most hospital-based situations. Therapeutic approaches - including interventional therapies and intra-arterial thrombolysis - are highlighted, including experimental agents and interventions where other treatment possibilities are limited. Increasing the awareness of such interventions is an important factor in reducing delays in the assessment of patients who have strokes while in hospital, thus decreasing morbidity and reducing costs.

Coronavirus Disease: From Origin to Outbreak provides a comprehensive review of coronaviruses, particularly COVID-19, its transmission, and disease pathology. The book covers the viral structure and genetics of coronaviruses, the pathogenesis and unique characteristics of coronavirus infection, and the evolving nature of our understanding of coronaviruses and disease. It also looks at the history of SARS-CoV and MERS-CoV infections and its global spread. The book examines the effectiveness of various preventive measures and new therapeutic agents that are either currently available or expected to available. Finally, it details the psychological and societal impact the virus and disease has in outbreak regions and what the financial impact an outbreak has on the healthcare system and local economies.

Dengue Virus Disease: From Origin to Outbreak provides a detailed accounting of one of the world's fastest growing infections. According to the World Health Organization, Dengue virus incidence has increased 30-fold over the past 50 years, with up to 50 to 100 million infections occurring annually in over 100 endemic countries. This estimate puts nearly half the world's population at risk. This book reviews the history, clinical and diagnostic aspects of dengue virus, also presenting our current knowledge on the pathophysiology of severe dengue and addressing the importance of dengue virus infections in those traveling to parts of the world where it is endemic.

Zika Virus provides an authoritative account of one of most fascinating viruses of the 21st century, covering all the main points. It includes coverage of clinical manifestations, such as fever and fatigue, but also delves into neurological manifestations like acute demyelinating neuropathy. In addition, the book discusses new evidence that suggests that Zika fever in pregnant women can cause abnormal brain development in fetuses by mother-to-child transmission. The Zika virus infection has become one of the first where women are actively discouraged from getting pregnant. Readers will find this book to be a comprehensive resource on the topic.

Ebola Virus Disease: From Origins to Outbreak covers Ebola virus disease in its entirety from its origins through major outbreaks in the past to the present day outbreak. It contains information on the West Saharan response to Ebola as well as highlights from the field in West Africa from Dr. Qureshi and Dr. Chughtai, helping to solve the primary question of what's next and aiding in formulating a path forward. With a growing awareness of the devastating effects of this viral disease and an influx of topical research, this book provides the information the global community of researchers, clinicians and students need to better inform their research and study of Ebola virus disease.

This book provides a framework for goal-targeted management of the adult patient with spontaneous non-traumatic intracerebral hemorrhage (ICH). Topics addressed in a comprehensive yet practical manner in the book include pre-hospital/emergency department care, early inpatient work-up, antithrombotic- and thrombolytic-related strokes, optimal blood pressure management, avoidance of medical complications, surgical interventions, outcome prognostication, recurrence prevention, rehabilitation/recovery, special situations, systems of care, and the design of clinical trials for patients with ICH. Procedures, processes, and helpful decision-making algorithms are presented with the aid of complementary illustrations that facilitate understanding of practical aspects and enable the reader to promptly retrieve relevant information. In addition, the most current evidence-based therapies for routine management of ICH patients and a glimpse of promising future treatment strategies are reviewed. Timely and consolidated, clinicians will find this to be an indispensable resource to navigating the ever-increasing pace of discovery that is transforming what we know about ICH and its treatment.

Endovascular intervention - using medication and devices introduced through catheters or microcatheters placed into the blood vessels through a percutaneous approach - has emerged as a relatively new minimally invasive approach to treat cerebrovascular disease and possibly intracranial neoplasms. This textbook provides a comprehensive review of principles pertinent to endovascular treatment of cerebrovascular diseases and intracranial tumors, with a detailed description of techniques for these procedures and periprocedural management strategies. Particular emphasis is placed on expert interpretation of the quality of evidence provided and implications for practice related to endovascular procedures. This will be essential reading for clinicians working in interventional neurology and cardiology, endovascular neurosurgery, vascular surgery and neuroradiology.

Neuroendovascular and neurointerventional therapy is a specialty where disseminating personal knowledge and expert opinion is extremely important, owing to the lack of large-scale clinical trials. The management of complications that occur during or immediately after therapeutic interventions is particularly challenging because these can significantly affect patient outcomes. This book presents how various complication scenarios are handled by well-qualified authorities in the field of neurointervention from three disciplines: neurology, neurosurgery, and neuroradiology. Contributors describe their management of these complications, focusing on the common principles that all the specialists agree on, and give tips and tricks for 'bailout' procedures to help get the practitioner out of trouble. The book is well illustrated and covers the full range of neuroendovascular and neurointerventional procedures. The book will appeal to neurointerventionists, neuroradiologists, stroke physicians, neurosurgeons and vascular surgeons for its practical approach to managing these commonly encountered problems.

Nine out of every ten medical students, residents, and fellows attempt to write a manuscript during their training. Yet, after finishing the training only 1 or 2 would continue to write scientific manuscripts due to the effort involved in preparing a manuscript. Most medical students, residents, fellows, and even junior faculty consider writing a scientific manuscript harder than working grueling hours on the clinical service. The manual of scientific manuscript writing was developed to guide for medical students, residents, fellows, and junior faculty by providing a step by step pathway for successful preparation of a manuscript. The manual is expected to reduce the usual 3 and 6 months (at times frustrating) effort to a 1 to 2 week streamlined process to complete a manuscript.

Quotations are like tools, gauges, meters, warning lights, instruments and controls, which are essential for the smooth operation of our life's vehicle. Because of their depth and poignancy, they serve as palatable cooked-and-packaged food, and save us the hassle of collecting ingredients and cooking them ourselves. The minimum they do for us is to widen our list of options to handle different situations of life and be better prepared for all eventualities.